The differences found seem more interesting:

>The study also found differences in gut bacteria between coffee drinkers and non-coffee drinkers, including increases in species such as Eggertella sp and Cryptobacterium curtum, which are thought to play roles in gut function and metabolism.

>Cognitive effects varied depending on coffee type: decaffeinated coffee was associated with improvements in learning and memory, while caffeinated coffee was linked to reduced anxiety, improved vigilance and attention, as well as a reduced risk of inflammation.

The actual journal article has a lot more information, the clickbait headline doesn't really do it justice https://www.nature.com/articles/s41467-026-71264-8