| ▲ | catigula 9 hours ago | |
I’ve been taking high doses long term for over a decade and I don’t really have any substantial issues. | ||
| ▲ | mapkkk 2 hours ago | parent | next [-] | |
Definitely not a good idea to be on it longer than 2 months. If we can't treat the underlying condition and the patient needs life-long acid suppression therapy, we switch to H2 receptor antagonists, like cimetidine. Long term PPI use has non-trivial risks, including magnesium and other micronutrient deficiencies, and can lead to things like SIBO and other primarily gut related morbidity. I would definitely suggest sitting down with your doctor if you were not specifically instructed to take it for that long. | ||
| ▲ | derekja 8 hours ago | parent | prev | next [-] | |
The primary concern is reduced stomach acid leading to nutrient deficiencies, particularly b12. There have been some long term studies correlating to dementia as a result. And some studies that have not found this. So the jury is still out, but keeping an eye on some nutritional markers is not a bad idea. | ||
| ▲ | dotcoma 8 hours ago | parent | prev [-] | |
Good for you, but this mere fact does not mean it’s ideal. Not a doctor, but I would at least try to look into this. Best of luck! | ||