I'm curious how you handle that.

Let's say I operate with a 4 decimal expectation and your API expects 6, is there any way to reconcile that outside of documentation and or metadata ? (which would be the same issue I guess whatever representation is used ?)

Yeah, you need to document it.

Still, even if you do: Chances that your users are just going to assume you're conforming to ISO 4217, some national standard, or your competitor that they're already integrated with are pretty high, so I wouldn't take the chance. Pick something that doesn't have to be documented instead.