Until prices hit the large hyperscalers, I don't think most people are going to make significant changes. You might see a small set of open source projects related to self hosting put in an effort, but in general, I don't think so.

Some big-tech orgs (that have their own hardware) will take costs into account, but they already do that. The "optimization" is more likely to be business-optimizations; "this can be slower if it uses less memory", rather than inventing new stuff.

Note that I am excluding any of the big AI labs. They are definitely going to be working to figure out how to use less memory, but that's primarily not related to the direct cost.