That to me looks like Reticulums [1] adressing ("Destinations") with transport done via QUIC. Does it add anything what Reticulum didn't already solve, other than using slightly different protocols - do they have an advantage?

[1] https://reticulum.network/

Besides the novel/different form of addressing Reticulum pretty much imposes its Zen on users. So in a lot of things where Reticulum is quite dogmatic, something like Iroh I'd assume (if it's reaching corporates) would provide more flexibility. I haven't checked out the source though.

As an example, AFAIK, Reticulum encrypts packet origin, so only recipient can see them. I don't think this is admissible in a corporate network.

Or I2P that even comes with reinforced privacy: https://i2p.net/en/

This is the comment I was about to make. Reticulum is already a very complete network stack.