I am not going to say that I agree with OP, or that OP's language isn't entirely too casual for someone close to this issue but it appears they're most focused on finding out why people have a different inner self than outer expression.

We recognize that the inner self's gender is unalterable (and if it weren't, I'm not sure I'd be comfortable with that sort of mind control), so we must bring the outer in alignment.

However where the inner self gender comes from is something I'm not sure we know too well. Is it the womb? Is it early childhood development? Do hormones and nutrition affect this process which we haven't even pin-pointed in anyway?

Personally, I think it's too early to call out chemicals as a cause. That's a bet we can't take until at least we know the process. And if we're at that point, we could do that mind control that I'm so much against.