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ragequittah an hour ago

Many of the research went under my radar when I was researching it ~15 years ago then. Specifically sucralose was what I was researching, because it's what I drank, and there seemed to be no real evidence of harm that I could come up with or that anybody arguing with me about it could point to. And everyone defending it (including me) always had the line about how extensively studied it was at the time.

But research kept coming in. In 2013 CSPI changed their sucralose recommendation from "safe" to "caution". Then in 2016 it changed it again to "avoid". [1] Insulin sensitivity was more of a concern as of 2018 [2]. Sucralose + carbs causing further insulin problems was added in 2020 [3].

There's several more but I'm not going to make an exhaustive list. The point is the more research done the more the sweeteners go from almost completely benign (which you could easily say about sucralose ~2010) to problematic. So saying "the science is in, these sweeteners don't cause cancer" seems off-putting to me after going through the journey of so much of the science being wrong. It reminds me that we didn't classify processed meat as carcinogenic until 2015. And we only classified nitrates as "probably carcinogenic" in 2010.

[1]https://www.cspi.org/new/201602081.html

[2]https://pubmed.ncbi.nlm.nih.gov/30005329/

[3]https://pubmed.ncbi.nlm.nih.gov/32130881/