...HSV would be extremely low on my list.

I think this is a bit of an unfair conclusion.

First, while you're correct that most people who have HSV have few symptoms (if any), you're discounting the fact that, because so many people are infected, there are millions upon millions who have highly-visible and highly-painful infections. Many of these people struggle with relationships and mental health as a result.

Second, HSV is associated with higher risk of HIV infection for obvious reasons.

Finally, discovering effective treatments for such a difficult virus would probably produce insights that have implications for other difficult-to-target viruses.

So I don't think we should dismiss HSV on the basis that it's so common and doesn't cause life-threatening symptoms. Medicine should pay adequate attention to infections that affect quality of life for large numbers of people.

Billions are spent on treatments for super rare diseases, many of which are terminal, and in the best cases the end result is often that pharmaceutical companies have drugs costing tens or hundreds of thousands of dollars that extend life by months (often with dubious quality of life).