| ▲ | senkora an hour ago | |
I just skimmed the summary but in the results section it reports three significant results and two after “multiple-test correction”. I’m not sure how they did that correction; I would expect that measures of cognitive performance are correlated for each child and so the standard Bonferroni correction might be too harsh to apply here. > Covariate-adjusted analyses of standardized scores (mean [SD], 0 [1]; higher values indicating better performance) showed positive associations of high-dose vitamin D3 with verbal memory (β = 0.17 SD; 95% CI, 0.03-0.32 SD; P = .02), visual memory (β = 0.24 SD; 95% CI, 0.06-0.42 SD; P = .01), and flexibility or set shift (β = 0.19 SD; 95% CI, 0.01-0.37 SD; P = .04); however, high-dose vitamin D3 was no longer associated with flexibility or set shift after multiple test correction. | ||
| ▲ | tdb7893 35 minutes ago | parent [-] | |
My statistics isn't great but reading the study more it looks like they control the rate of false positives via the q values so my initial concern may be unwarranted. I'm surprised that it keeps so many barely significant results with so many hypotheses. I'll have to look it up when I get time. | ||