The whole "state rights" thing has traditionally been to allow states to do shitty things, but there's value in having freedom to experiment too.

I believe that regulations in general serve us well, but they can be onerous. We then fall into each side talking past each other with one advocating for more regulations and the other for no regulations. I think the way to address this is for the pro-regulation side recognize resulting burdens and actively work to mitigate the pain rather than just take a "not my problem" approach.