Air filtration is one of the hardest things do deal with in space.

I don't know what solvents would do, but I remember that astronauts' bone density loss in space means there are challenges around managing the significant amount of calcium captured by the air scrubbers in the ISS.

Do they literally sweat their bones away? I can imagine how it would work on molecular level via sweat / breathing, but I would expect >99% to be simply pissed and shat away.

Wouldn't the calcium go out in your urine?