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smj-edison 2 hours ago

Thanks for the link! I looked over it, but I'm not seeing quantitative levels of reactions. That's been my biggest issue with current pathway databases. It's great to know what's connected to what, but very quickly it becomes everything connected to everything. And unfortunately everything doesn't reduce the problem space.

gilleain 38 minutes ago | parent [-]

That would be difficult - a metabolic map is a diagram showing the known reactions. At any point in time, only a subset of these will be active. Like a road map - at midnight, only some roads will have traffic.

I think what you are looking for is more like a model of the metabolome, showing the flow through the network under certain conditions (steady-state, growth, cell stress, etc). Not sure if there is a readily available database of such models, or how easy it would be just to run them and get meaningful results.