I've worked 12 years at Google. When I was tech lead, I periodically checked Memegen and searched for my project name. I found it useful to get this feedback. Sometimes I converted the meme into a proper bug report; sometimes I responded to the meme with an explanation.

Not everyone will use Memegen in the same way. But quite often a high voted meme can be treated like a high voted bug report. It provides signal to the team.

Note that I worked on internal tooling. External facing teams have lots of other feedback channels, and they know that Googler's feedback is biased. So how the team responds to the feedback can be vary a lot.