Funny because I'm not sure I quite notice it immediately when I stop taking it, presumably since the body retains a certain amount of it. But I definitely notice a difference when taking it the first day after not having had it a little while, especially when taking 20+ grams a day. It gives me so much mental energy and alertness that I won't get a whole lot of sleep, but the next day I end up feeling just fine. If I remember correctly, there have been at least 2 studies that suggested high doses of creatine reduce the side effects of suboptimal sleep, and that definitely seems to be the case in my experience.

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boredemployee 2 hours ago | parent [-]

Isn't 20+ grams a day a lot for the kidneys? genuine question

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yesb an hour ago | parent | next [-]

Elevated creatinine levels (in absence of supplementation) is a sign of kidney issues. There are many studies showing no reverse link i.e. supplementing creatine damaging kidneys

https://link.springer.com/content/pdf/10.1186/s12882-025-045...

	▲	dev1ycan 3 minutes ago \| parent [-]
		Okay but logically kidney issues leading to high creatine does suggest that creatine is not all that good for the body, no? else why would the kidney keep it under control?

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unshavedyak an hour ago | parent | prev [-]

Not the parent, but someone else commented on this: https://news.ycombinator.com/item?id=48347735

	▲	an hour ago \| parent [-]
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