There's an ETF for everything out there. (There are more ETF's than stocks). There'll be a large market for "S&P500 without SpaceX" et al, so it's seems likely somebody will fill it. It probably will have to use a worse name because of the S&P trademark.

P.S. Here's an example of S&P500 without the magnificent 7 https://www.defianceetfs.com/xmag/