LTO cannot change the layout of structs. For something like a hash map implementation, it matters whether inner nodes store a pointer to the key and value, or whether it stores a pointer to each. To achieve this in C, you have no other options than emulating templates using macros.

The question is whether a hash-map implementation that works on a general `[key, index]` item and where index references at separate array of values isn't actually better for some access patterns ;)

And of course the other alternative to macros is code-generation (but macros are actually often fine).

But this also only matters for actually reusable generic code. If I'd implement a super-hot-path hashmap in C, I would stamp out a specialized version by hand instead of relying on a generic implementation. But for 90% of cases, a solution like in stb_ds.h is probably good enough.