Paradoxically, nicotine has some medical use in e.g. displacing viral debris and autoantibodies from nAChR (nicotinic acetylcholine receptors) due to having highest affinity to these receptors, which seems to help with (long) Covid; "smoker paradox" in lower covid-related hospitalizations.

Special attention to this comment - I’ve been closely tracking this regarding individuals close to me.

Great to see this here.

There’s no paradox at all - CIGS are bad, nicotine is pretty neutral to good,

as a lozenge or patch or gum.