When "Resident Alien" came out, we started watching it and I quipped to my wife, "oh, so this is 'Northern Exposure', but the out of touch, out of towner doctor pressed into small town service, constantly scheming to get out, is more likeable."

There is a touch of Mork and Mindy to Resident Alien too. But yes, I do see a bit of Northern Exposure in Resident Alien, and in Due South which popped along a few years later...

And a touch of Twin Peaks in Northern Exposure itself.