No, policy wise I appreciate you getting into the nuance, but I feel like you take the argument to polar extremes (with an attitude of confident, final certainty), when the expected outcome is across the middle. This smells more like ideology than practicality.

> These discussions always end up …

Before your comment i wouldn’t say anyone is lacking curiosity here. Tho your comment about fixing into a stereotype, seems the example of itself. I think it’s better to listen and discuss than assume the futures settle into a mischaracterization that you’ve already decided. That doesn’t seem very useful - except for ideology…

On the toxicity side, do you have any studies to cite? I wasn’t aware of toxicity, but it’s plausible.

Big picture tho, I’m not an expert in drug policy. It just sounds like a logical way to reduce harm overall. Reduce harm overall - worth repeating; on average, create a better society.

The conceivable parties who would lose out are: government funded agencies charged with fighting drug crime because their caseload and budgets would probably decrease; and on the other side the cartels and dealers. Although what seems to happen with the latter is once something is legalized, the supply chains morph into legitimate businesses somehow.

I still think it would work. I’m not convinced by what you said. Thank you tho

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cyberax 25 days ago | parent [-]

> On the toxicity side, do you have any studies to cite? I wasn’t aware of toxicity, but it’s plausible.

A typical therapeutic dose of amphetamines is around 20mg, topping at around 60mg for serious narcolepsy. Recreational doses can go up to around 1000mg for long-term users with 360mg as the median: https://pubmed.ncbi.nlm.nih.gov/40385390/

That's the area of crazy toxic side effects just from vasoconstriction. Never mind direct effects on the brain.

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keepamovin 25 days ago | parent [-]

Okay, I remember seeing a documentary where people were doing lines of methampheatmine. And typically people would do 2 to 3 lines and be up all night. I would consider a line a "small amount".

If I could go to a regulated dispensary and do a line of methamphetamine I think I'd try it. I don't think it would be neurotoxic, but I'd be very interested to know data that supports that, obviously! If you have, please show.

The doses you are describing I think fall outside responsible recreational use and into other categories - that sound more like poisoning / overdose.

A problem of criminalization is that society seems to tend to bucket all illegal drugs into a single category of usage misrepresented by the worst doses. It is possible for people to use these substances responsibly. And with assistance on purity, and regulated access, I believe the chances are high.

The regime I am proposing should even make it easier to deal with the % of people who bucket into overdoese/poison territory.

I'm not sure how much 1 line contains, but to me it seems as if it would be 50mg?

	▲	gruez 24 days ago \| parent [-]
		>If I could go to a regulated dispensary and do a line of methamphetamine I think I'd try it. You can, it's called getting an ADHD diagnosis through a telehealth provider, which gets you an adderal prescription. It's not literally meth, but for all intents and purposes it's equivalent.