I believe OP wanted to make the point that one of the most important things for people profiting from the illegal sale of drugs (meth or heroin/opiates) is to minimize the amount that has to be trafficked (1kg of 10% meth vs 100g of pure meth or 1kg of heroin vs 10g of fentanyl).

I believe this explanation is too simplistic...

yes, the "Iron law of prohibition" https://en.wikipedia.org/wiki/Iron_law_of_prohibition

"the harder the enforcement, the harder the drugs."