I mean, sure, in the set of things that one could put into my food surreptitiously, antibiotics is one of the better ones (I guess assuming that the spiker does the full regimen). I'll acknowledge that amoxicillin is better than a roofie.

It's still unbelievably scummy to infect your partner with a disease and then drug that partner because you're too much of a coward to come forward about it. Adultery is already bad, infecting your partner because of that adultery is bad, drugging them to cover it up is bad.