I use CP-SAT for automated design problems. I need a guarantee on solution quality, so gen AI is a nonstarter. The problem formulation is quite messy and has constraints that can vary by locale. CP-SAT handles it pretty well.

The one thing I've been trying to model well are cover constraints where for each x : xs, there is some y : ys st. pred(x, y). I've tried both boolean matrices and index constraints, and they work but seem to be quite taxing on the solver. Maybe there's a better formulation.