IMO Obsidian is currently the king of "personal software frameworks". You can look at YT channels for inspiration of what other people are doing, but I'd avoid trying to copy someone else's setup (for the vague promise of productivity), and instead just start to tinker and tailor your environment to yourself. The base experience is really good. What matters most is that you spend time actually writing useful things down.

For personal use - Obsidian + AI (claude code / codex) + self-authored plugins is the best AI experience available. Folks like Karpathy have been writing a bit about LLM-powered wikis and context management. That seems to be causing a big wave of interest at the moment.

What I see from our business customers is all about AI in a collaborative context. The more advanced customers are typically developing an in-house plugin for their agent so they can make setup really easy, centralize token tracking, and aggregate learnings (while respecting employee privacy/customization). We also see strong interest in the privacy/security aspect from red teams (trying to track the huge influx of vulnerabilities).

IMO the practices for using Obsidian effectively in a work environment are under-represented on YT and in tutorials (we have done some light consulting in this area).

(I'm the developer of Relay / https://relay.md )