Are there any supplements that can work for neurogenesis? I've heard Lions Mane extract can do this, but I'm not sure. Anybody know of anything?

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RobotToaster 23 minutes ago | parent | next [-]

Supposedly NGF eye drops https://www.independent.co.uk/news/science/is-this-the-secre...

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toasty228 4 hours ago | parent | prev | next [-]

If you don't sleep 8+ hours a day every single day, exercise regularly, live in a place with clean air, eat clean food, don't drink alcohol, etc. you're losing your time, no amount of supplement will make up for our modern way of life, you're going to optimise the 0.1% while missing the 99.9% that matters

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SilentM68 3 hours ago | parent [-]

That is true, but keep in mind that routine is very difficult to do for someone that makes their living running the rat race, with stress, no time, responsibilities, worry, untreated health problems, etc. If you have the money, job security, then you'll have peace of mind. That will then allow one to live that kind of optimized lifestyle.

	▲	rexpop 3 hours ago \| parent [-]
		This is why we cannot abide scabs.

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throwforfeds 4 hours ago | parent | prev | next [-]

There's (minimal) research on psilocybin doing just that. One of the tragedies of prohibition is that we just weren't able to study these psychedelic compounds easily for 50+ years.

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grvdrm 2 hours ago | parent [-]

Have any sources? I’d love to read what you are thinking about.

I haven’t used psilocybin in a clinical setting but have gone through an alternative psychedelic-assisted therapy process. Very interesting results and many positives.

	▲	sowbug 32 minutes ago \| parent [-]
		Not necessarily neurogenesis, but evidence of neuroplasticity: https://news.ycombinator.com/item?id=48030098

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dirtbagskier 4 hours ago | parent | prev | next [-]

Cardiovascular exercise and strength training. Both are thought to contribute to neurogenesis, even in healthy people

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NDlurker 3 hours ago | parent | prev | next [-]

Noopept

https://en.wikipedia.org/wiki/Omberacetam

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aeonik 3 hours ago | parent | prev | next [-]

Alpha-GPC and Uridine Monophosphate appear to have some effect, though minor. Also not exactly neurogenesis, but adjacent stuff. Evidence is complicated, there seems to be a signal but it's a weak effect.

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caycep 3 hours ago | parent | prev | next [-]

Of note, cautionary tale is too much neurogenesis is brain cancer...

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dymk 3 hours ago | parent [-]

No, brain cancer is brain cancer.

	▲	caycep an hour ago \| parent [-]
		which is poorly differentiated cells undergoing unchecked neurogenesis...

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sysreq_ 3 hours ago | parent | prev [-]

Nicotine is the only psychoactive substance proven to increase intellectual function. Rote neurogenisis does not - much in the same way height isn’t a proxy for IQ. Stimulants like Adderall, Caffiene, etc are Dunning-Kruger by proxy.