There's nothing forcing you to use Chrome instead of Edge, but some websites don't work with Safari or Firefox because Google has pushed nonstandard stuff. And it's weirdly not only advanced WebWhatever stuff, but also some things that affects basic features like forms. Though sometimes they have a separate mobile site that was tested in iPhone Safari.

I find the discrepancy kinda minor though. It's enough that I have Chrome installed alongside Firefox and Safari, but not enough that I use it often. It used to be worse.