They already donate a lot of useful money via the Chan Zuckerberg Institute so there’s a good track record at least

Chan Zuckerberg Institute doesn't produce much actual research it's mostly fancy dinners, global travel for congresses and conferences and big opulent parties. They actually got in trouble in the building with the landlord for too many parties, there was a problem drunken individuals peeing in the hallways when they had Justin Bieber and other celebs on site (seriously).