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cookiengineer 11 hours ago

...because Alzheimer is a dormant side effect of a virus, not of a messenger chemical. But that doesn't go well in studies and "self populism" of what funded research wanted to hear.

If you study effects and not causes due to lack of measurements for reproducibility in any field of research, that's what comes out.

Also check out how the new and promising correlation started by observing the Wales eligibility for mandatory shingles vaccination during an outbreak and the effect on that test group when it comes to alzheimer or dementia in their old age.

Note that shingles (herpes zoster) virus is a dormant virus for decades, and it's not really treated because of that.

Also note that this was only discovered because people died and their data set was publicized because of that, which I hope that can happen in an anonymous way due to it being invaluable for medical research.

[1] https://www.alzheimer-europe.org/news/analysis-electronic-he...

[2] https://pmc.ncbi.nlm.nih.gov/articles/PMC11485228/

[3] https://www.sciencedirect.com/science/article/pii/S009286742...

[4] https://www.alzforum.org/news/research-news/shingles-vaccine...

anon84873628 10 hours ago | parent | next [-]

Gee, that sure is a confident statement of fact.

Or maybe virus activity is one way that a negative feedback loop involving protein aggregates can begin...

nickburns 9 hours ago | parent [-]

Sure is a line of inquiry worth pursuing either way, no?

josh-wrale 10 hours ago | parent | prev [-]

Not always. Genetic causes are known.

cookiengineer 5 hours ago | parent [-]

... which kind of points to the indicator that "Alzheimer != Alzheimer", implying that too many diseases with the same side effects are categorized together?

A lot of virological and parasitical components have historically been wrongly associated with genetic markers, too. Toxoplasmosis parasite comes to mind.

[1] https://en.wikipedia.org/wiki/Toxoplasmosis

[2] https://en.wikipedia.org/wiki/Toxoplasma_gondii

josh-wrale 7 minutes ago | parent [-]

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