I think there's a lot of potential for some more old-school UI in business software. People using points of sale, CRM/ERP/PLM/etc. systems, intranet portals, and so on don't really care about how nice it looks. Efficiency is more important.

Especially if it can be easy for non-technical people to build efficient UIs and databases (so they don't have to resort to spreadsheet contraptions), I think there's an opportunity here...