I’m super interested in this sort of study! However, it looks like n=62 here, which I think weakens the results —they’re probably just useful as suggestions of possible effects. Also, any food is expected to have similar effects on the microbiome. They didn’t test caffeine in isolation. In some ways that’s better (I don’t consume caffeine in isolation), but in some ways that’s less useful (it’s possible you get similar results from many random vegetables)

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sixtyj 2 days ago | parent | next [-]

In 1995, NASA did spiders experiment. Caffeine is a siginificant impulsivity trigger. :)

https://rarehistoricalphotos.com/nasa-spiders-drugs-experime...

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ButlerianJihad 2 days ago | parent | next [-]

Warning: those photos in the dot-com website are negative images, not the original black-on-white. Lousy with animated ad banners, too.

https://ntrs.nasa.gov/api/citations/20100033433/downloads/20...

Don't ask me why some blogger posted the PDF in 2013, and also don't ask me how English Wikipedia editors determined that a Wordpress blog is a "Reliable Secondary Source". I did locate the original on NASA's own website. Public Domain (USGov).

	▲	Scipio_Afri 2 days ago \| parent \| next [-]
		What a find! It's on page 106 but I didn't immediately do a control-f to find it or look at the table of contents. My gosh, all the stuff I flipped through before that... some things haven't changed (e.g. Digikey and National Instruments ads).
	▲	khalic 2 days ago \| parent \| prev [-]
		Thanks for the time capsule. Boy that’s a lot of ads (live video on a computer! Wow!). The poor marijuana spider tried really hard

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ivell 2 days ago | parent | prev | next [-]

LSD has unconnected strands in the air. I guess this is expected.

	▲	dotancohen 2 days ago \| parent [-]
		The LSD and sleeping pills were not in the original study I believe. That might be an artists representation of the image at the bottom of the original study, which I remember showed the results in a single row.

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jayd16 2 days ago | parent | prev [-]

Nice web, Mr. Crack spider.

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bhaney 2 days ago | parent | prev [-]

> They didn’t test caffeine in isolation

But they did test both caffeinated and uncaffeinated coffee, and found the same effects in both, indicating that the effect is caused by something in coffee other than the caffeine

	▲	krige 2 days ago \| parent \| next [-]
		Doesn't decaf also contain caffeine, just a lot less of it?
	▲	anon84873628 2 days ago \| parent \| prev [-]
		Typical extraction yield is 18-20%. For a 20g dose that's 4g of material consumed, or about 30 individual beans. I wonder if you could find similar effects with 4g or broccoli sprouts, or garlic, or ginger, or cumin seed, shiitake mushroom, seaweed, soursop leaf, or...