All three of these suggestions are likely true. I’ve never done Ketamine but I’ve heard it can seriously degrade the user’s “quality control” of their ideas, meaning that ideas that they have, or ideas they get from others, that are intellectually subpar appear to be quite brilliant. The dissociation is also helpful for overcoming moral qualms if they were ever present.

Combine that with speed and a insular SV culture steeped in the ideology of Ayn Rand and Nick Land (who likely suffered from amphetamine psychosis) and you get something like this Palantir manifesto.

I would feel sorry for them if they weren’t building skynet.

I feel sorry for them because some of them will never wake up to experience life

And that's deeply sad to me