There is no physics based reason why it couldn't work. If the industry really wanted to do it they could. But they don't. The primary reason is LPDDR just has too many pins. A DDR5 SODIMM has 262 pins and is an unwieldy beast. LPDDR5 has 644 pins.

LPCAMM2 really shows the trade-offs. It adds a lot of bulk and cost, and repairability hasn't been valued high enough by the market to cover that overhead for most consumers. That's why Micron exited the market they played a big part in founding.

https://www.ifixit.com/News/95078/lpcamm2-memory-is-finally-...