Nobel Nacre.. The nobelprize is hyper destructive to the scientists receiving it. Its hard to one up from there or return to your field- everyone is bombarding you with high expectations. You can only fail after you received olympic gold. Thus, as scientists inflict change on society, and society hates change, it is like a oyster, trying to protect itself from a grain of sand, wrapping it in Nacre, protecting itself from further change, by encapsulating the changing factor which remains neutered from its ability to do science.

Nobel prize is usually awarded many years after the work was done and by the time its awarded the scientist is usually well past their prime