Separation of functions/concerns is not great, for starters.

The testes are dangerously exposed, the plumbing is convoluted and failure-prone (and doesn’t recover well from mechanical insults).

The prostate, which serves no function outside of reproduction, lies inline with the urethra and quite consistently loses flexibility and becomes enlarged with age, causing all sorts of structural issues impacting basic urological function.

Female reproductive vs urinary anatomy is largely physiologically distinct (proximity and UTI risk notwithstanding). Though plenty of room for improvement there too — starting with endometrial tissue being far too prolific. Fun fact: endometrial tissue can migrate to the brain and cause haemorrhaging in severe cases of endometriosis.

Plenty of room for improvement across the board, I’d say!