If you're looking to buy new hardware, also consider the Asus Rog Flow Z13. It has the same chip as the Framework desktop and is ~20% cheaper ($2,700) for the 128 GB spec while coming in a tablet/laptop form factor. It's capped at a slightly lower power but Strix Halo scales down very well in TDP - I never even use the max power mode on my Z13 because you don't really get any extra perf.
The only downside is that I suspect the Framework would be a decent bit quieter under load (not that this thing is abnormally loud). As well as you're limited to a single M.2 2230 internal SSD slot in this (I believe Micron recently launched a 4 TB model, but generally you'll max out at 2 TB without using an external enclosure).
I don't have anything against the Framework, I'm sure it's a great machine, but the Z13 is an incredible portable all-in-one device that can handle everything from general PC use to gaming to tablet/entertainment to LLMs & high perf.