I've often wondered - what is the exact amount of vacuum (pressure?) that you can get away with without disemboweling someone?

A possible point of comparison might be pool drain injuries (a/k/a suction entrapment), and some of these have disemboweled people, though largely children. Vacuum toilets in cruise ships have also been implicated in such incidents (see, among others, https://www.upi.com/Archives/1987/03/06/70-year-old-womans-i... ). A more, er, pressing concern in adults might be rectal prolapse.