Probably; if it has an API you can probably get coding tools to use it. But the point of using agentic coding tools is that they are really good at working with code and files. And it tends to be a lot faster and easier. And you can build tests and browser tests around that as well.

In my view, a CMS is intended for people doing stuff. If you transition that stuff to AI Agents, why keep the CMS around? And if AI does all/most of the coding, it's not such a big leap for non technical people to get their hands dirty anymore.