You can disable GC in tinygo, so if you allocate all the necessary buffers beforehand it can have good performance with real-time characteristics. If you _need_ dynamic memory allocation then no, because you need GC it can't provide realtime guarantees.

Doesn't seem like those should be mutually exclusive, though the habits involved are quite opposing and I can definitely believe they're uncommon.

E.g. GC doesn't need to be precise. You could reserve CPU budget for GC, and only use that much at a time before yielding control. As long as you still free enough to not OOM, you're fine.