Please do demonstrate the difference in this context.

Hormone expression. Muscle mass. Reaction time. Weight.

A YEAR of hormone therapy. Meeting a required measured threshold of testosterone.

And that's not even the controversial stuff. A man and a trans-woman are different. hell, one has (generalizing here) boobs: come on... don't be dense/obtuse! Have you tried running fast suddenly having boobs when you did not before?!?! ...one is way easier.