The article misattributes the cause of the public's loss of trust in science.

The public has lost confidence in science because commercial and political entities have worked systematically to undermine scientific authority that threatens their business models and narratives.

Fossil fuels, tobacco, and refined sugar single-handedly manufactured decades of scientific "controversy" around climate change, tobacco's health impact, and the role of sugars and fats in obesity and heart disease. Religious fundamentalists fund pseudo-scientific books and articles attempting to muddy the waters concerning geological and biological evidence about any time period before the invention of agriculture. Grifters fabricate arguments and data to delegitimize Western medicine to sell placebos at high markup. Politicians attribute all unflattering research to partisan skullduggery.

It is true that hard science, social science, and medicine all have published flawed work; sometimes even in bad faith. These occasional failures -- which should be corrected and never tolerated -- are then used by the same people to indict the entire enterprise.

It's true that there's research misconduct, and it must be weeded out.

What's also true is that funding for research is declining in the US, especially relative to our need for it.

Note how many "tweaks" center on things like sample-size or statistical significance. Human-oriented research is always intractably complex, and we get the scientific outcomes we do because studies are perennially understaffed and under-resourced relative to the questions they seek to answer. Trying to answer fundamental questions about health and wellness with 30 people tracked over 6 weeks is fundamentally flawed, but it's the best we can do with the resources we have.

In a world where funding was plentiful, and career paths not cut-throat and perilous, there'd be far fewer examples of these kinds of "tweaks." People respond to incentives, and if the options are "add a few more participants, because after all the initial sample size was somewhat arbitrary" or "fail to publish, fail to graduate, fail to get a permanent position after a decade of post-secondary education because applicants must be perfect," the only surprise is that they aren't more common.