I tried fedora silverblue for a while, but the way it works is that it builds a new root fs image whenever you change the installed packages, this makes system package changes take comparatively long vs a traditional os. They suggest installing most apps via flatpak, which is okay as long as you can deal with flatpak idiosyncrasies.

I also tried fedora coreos for a vm + container host, but found the recommended method to configure the system with ignition files and one shot systemd units to be too involved for making a one off system, and it’s probably better for a cloud deployment with many identical nodes.

In all fairness, Nix is similarly slow.