For pipelines in any language, putting one function call per line often works well. Naming the variables can help readability. It also makes using a debugger easier:

  let foos = foobinate(a, b, input)
  let bars = barbakize(c, d, foos)

> Naming the variables can help readability

It can, or it can't; depending on the situation. Sometimes it just adds weight to the mental model (because now there's another variable in scope).