I mean... Yeah. Alcohol is very well documented and even more widely used for exactly this purpose BECAUSE it works.

The side-effects are often terrible. This is also true for many widely-prescribed drugs, and has been even more true in the past. The folks I've known on MAOIs were pretty wrecked.

”The folks I've known on MAOIs were pretty wrecked.”

And then one must consider that tobacco smoke and coffee both contain high levels of MAOIs.