Especially since every GLP-1 study shows almost complete regain to original weight after stopping.

It’s like stopping a blood pressure medicine and then being surprised that people have more heart attacks afterwards.

The discontinued and paused groups in the actual study had lower BMI than the continuing groups - so it seems like this is at least partially independent of any weight regain.

Which makes sense since we have strong evidence for the GLP-1s providing significant protective benefit even without weight loss.