The dose makes the poison. Paracelsus knew that 500 years ago already! Meanwhile in 2026 The Guardian publishes such articles every day (microplastics detected somewhere in irrelevant amounts, also water is wet).

The problem is we don't know what "irrelevant amounts" means, which is especially concerning because:

1. Microplastics are pervasive and would be very hard to remediate

2. They seem to bioaccumulate over years, and potentially even transmit intergenerationally

3. We have mechanistic evidence of them interfering with some rather critical biological processes, but processes that would yield chronic issues rather than acute ones

All of this makes it both very important and very difficult to understand the relationship between dosages and possible health effects.

> Maximum concentrations reached 351 mg/kg, dramatically exceeding the 10 mg/kg limit