Conversely, an app using native toolkits (at least the Windows ones) will have better chances of running fine under Wine. I've recently had the (dis)pleasure of trying to run some .Net monstruosity with Wine, and oh my got did it not work for obscure reasons.

But overall yeah, from a compatibility perspective, nothing beats Electron. I'm not sure we'd ever get an official Discord client on Linux otherwise.

Now if only Wine would work natively on Android