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jyscao 3 hours ago

Presumably this hypothesis is meant to explain why there is this observed asymmetry in the type of Neanderthal DNA we find in modern human populations that contain them, which is entirely autosomal. With none in the mitochondrial form, which is exclusively passed down along the female line, and also none in the Y-chromosome form, which is exclusively passed down along the male line.

Without weighing on the validity of their hypothesis that one or both sides found the other“especially attractive”, an alternative mechanism that could explain why we only see Neanderthal autosomal DNA in modern humans could be that only the female offspring of male-Neanderthal and female-sapiens pairings were reproductively fertile. This is more commonly the case in interspecies hybrids, see Haldane’s rule.

microgpt 3 hours ago | parent [-]

why no mitochondrial then?

jyscao 3 hours ago | parent [-]

Because these hybrids would contain mtDNA from their human female line. Neanderthal mtDNA could only be passed down by Neanderthal females.

And because none of those are found in any modern human populations, we can conclude no humans today are descended from female Neanderthals. Though whether hybridized descendants from male-sapiens female-Neanderthal pairings never existed, or they did exist for some time then eventually went extinct, we cannot currently say with certainty.

vintermann 30 minutes ago | parent | next [-]

Strictly speaking we don't know that. It may always turn up an extremely rare Y or mtdna variant which was thought to be extinct. Ötzi's mt like was thought to be extinct (Wikipedia page even still says so) but very recently a North African man took a full mtdna test and it turned out he had the same. That could happen with neanderthal variants too for all we know.

jjtheblunt 3 hours ago | parent | prev [-]

> we can conclude no humans today are descended from female Neanderthals.

that looks worded wrong, strictly speaking. if there's a male neanderthal ancestor, then he very likely has a neanderthal mom or grandma or ... great^N grandma for some N.

jyscao 2 hours ago | parent [-]

Ok yes, you're right. Guess I meant to say: no humans today are descended from someone between a male sapenis-female Neanderthals hybrid.