One significant difference is that all programming languages, whether machine code or python, have always been a precise language for describing the desired computation or algorithm. Working with an AI agent means specifying what you want the program to do in English, which is not precise. Unless you write English pseudocode.

(Yes, I know the compiler does wild stuff behind the curtain, but unless you're using -Ofast, the assembly is black-box-equivalent to a naive compilation)