ISP level blocking is for the mainstream, anyone slightly tech literate can overcome it.

The domain seizure, forced service shut downs like app store distribution ban or payment processing ban or forcing hosting providers not to serve you and physically taking you into custody for spreading unlicensed content is the real deal and it’s actually effective.

Though even if there is a way to circumvent, if there is no audience or ad revenues, there is no motivation. Look at Twitch streamers or YouTubers who are banned:

    -> No revenue
    -> No audience
    -> No reason to continue
    -> "Problem" solved