Honestly I'm not sure how good is LLVM's support for AMD GX11 machine code. It's a pretty niche backend. Even if it exists, it may not produce ideal output. And it's a huge dependency.

Quite good, it’s first party supported by AMD (ROCm LLVM, with a lot upstreamed as well) where it’s fairly widely used in production.

This project is a super cool hobby/toy project but ZLUDA is the “right” drop in CUDA replacement for almost any practical use case.