I mean, you say that, but systems like Spanner exist & I think the fact that it's used for Gmail, Docs, etc. has demonstrated that for a large range of OLTP workloads, serializable everywhere and also performant /is/ possible to architect for -- with the right combination of both database + application design.

That isn't to say it's correct everywhere, but I'd maybe be a little more suspicious of "We want OLTP but we can't use serializable" in a vacuum.

Of course--there are obvious cases like "We can't use serializable because of how our database implements it" or even "because we can't be arsed to figure out how to structure all our data accesses to avoid conflicts and aren't paid enough to solve that problem", but I feel like those are a bit more honest than "Because of performance reasons, in all cases". :)